6+ Bedroom Homes in Key Biscayne, FL
16 for sale · 18 homes listed · Updated November 9, 2026
- 420 Island Drive, Key Biscayne 33149 $12,485,000 · 6 bd · 8 ba · 6,405 sqft
- 31 Island Drive, Key Biscayne 33149 $9,800,000 · 6 bd · 7 ba · 5,826 sqft
- 110 Hampton Lane, Key Biscayne 33149 $6,900,000 · 6 bd · 7 ba · 3,550 sqft
- 741 Harbor Drive, Key Biscayne 33149 $7,390,000 · 6 bd · 7 ba · 4,043 sqft
- 120 Knollwood Drive, Key Biscayne 33149 $19,450,000 · 6 bd · 7 ba · 6,208 sqft
- 238 Buttonwood Drive, Key Biscayne 33149 $8,500,000 · 6 bd · 7 ba · 4,190 sqft
- 425 Harbor Drive, Key Biscayne 33149 $7,450,000 · 7 bd · 9 ba · 4,565 sqft
- 650 Curtiswood Drive, Key Biscayne 33149 $5,199,000 · 6 bd · 5 ba · 3,498 sqft
- 241 Cape Florida Drive, Key Biscayne 33149 $27,900,000 · 8 bd · 9 ba · 9,159 sqft
- 544 Warren Lane, Key Biscayne 33149 $8,000,000 · 6 bd · 6 ba · 1,044 sqft
- 131 Cape Florida Drive, Key Biscayne 33149 $16,500,000 · 6 bd · 7 ba · 7,103 sqft
- 110 Reef Lane 10, Key Biscayne 33149 $11,750,000 · 7 bd · 6 ba · 5,074 sqft
- 315 Cypress Drive, Key Biscayne 33149 $7,599,000 · 6 bd · 8 ba · 3,980 sqft
- 360 Harbor Lane, Key Biscayne 33149 $9,950,000 · 6 bd · 6 ba · 4,341 sqft
- 550 Harbor Drive, Key Biscayne 33149 $19,450,000 · 7 bd · 8 ba · 6,497 sqft
- 1080 Mariner Drive, Key Biscayne 33149 $19,750,000 · 6 bd · 7 ba · 6,468 sqft
- 165 Hampton Lane, Key Biscayne 33149 Active Under Contract $8,250,000 · 6 bd · 9 ba · 3,842 sqft
- 111 Reef Lane, Key Biscayne 33149 Sold on Aug 7, 2026 $11,500,000 · 7 bd · 6 ba · 5,008 sqft